Seth is an aspiring wizard from the Pompo Hills region. Like all wizards, he is one of the "infected," a select group of living beings who survived their encounter with the Nemeses: mysterious creatures from the sky that contaminate and decimate everything they touch. Seth's apparent immunity has led him to go on the offensive and attempt to fight these Nemeses. But more than that, Seth is set to embark on a quest that goes beyond hunting monsters. Alongside his friends and allies, he will travel the world in search of the Radiant—the alleged birthplace of the Nemeses—while trying to stay a step ahead of the dreaded Inquisition.